Brookshire Cypress Fulshear Jersey Village Katy Tomball Richmond
1.9K Reviews    |   
4.7 Star Rating    |    20+ years of experience    |    75k+ Patients Treated
Call
Add as preferred source

Trulance - Plecanatide

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Trulance
Generic Name
Plecanatide
Drug Class
Osmotic Laxative
Availability
Prescription
Manufacturer
Salix Pharmaceuticals
Indications
Constipation
Type
Tablet
Doses
3 mg once daily
Route
Oral
Side Effects
Diarrhea, bloating, abdominal tenderness, flatulence
Interactions
No known significant interactions; localized GI effect
Overdose
Overdose may cause severe digestive symptoms and electrolyte imbalances.
Missed Dose
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Contraindications
Pediatric patients under 6 years (risk of dehydration), known or suspected GI obstruction
Alternatives
Linaclotide, Lubiprostone, Prucalopride
Co-Pay Assistance Program
Available
Patient Assistance Program
Not available

Frequently Asked Questions

What is Plecanatide used for?

Plecanatide is applied in managing chronic idiopathic constipation and irritable bowel syndrome with constipation (IBS-C).

How does Plecanatide work?

Plecanatide acts by secretion of increasing fluid in the intestines and increasing motility, which overcomes stool softening and promotion of bowel motions.

What are the most popular side effects of Plecanatide?

The typical side effects are nausea, diarrhea, stomach cramps, and bloating. These are the side effects that, with time, the body can get used to and they pass.

What is the route of Administration of Plecanatide?

Plecanatide is normally administered orally in tablet form one time a day. The proper dosage will depend on your health condition that your healthcare provider will decide.

Plecanatide in Pregnancy Plecanatide does not have any effect on pregnant women.

Plecanatide is not to be administered in case of pregnancy unless this has more benefits over the risks. It should be used only when pregnant and with the help of your health practitioner.

What happens in case of missing the dose of Plecanatide?

In case you miss one dose, take it immediately when you remember to take it unless its nearly time to take the next dose. Do not take two doses at once.

Is Plecanatide advisable to be used with other drugs?

Most medicines are usually safe to take together with plecanatide although always tell your medical practitioner about all the medications that you are taking.

Please, tell me how long it takes Plecanatide to act?

The onset of plecanatide effect takes around 24-48 hours though it might take even longer in certain cases such as those of IBS-C.

Is Plecanatide to be used as a treatment of diarrhea?

Plecanatide is not normally utilized in diarrhea. When used, it affects the intestines and produces more fluid secretion that may aggravate the symptoms in patients with diarrhea.