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Remicade - Infliximab

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Remicade
Generic Name
Infliximab
Drug Class
JAK Inhibitor
Availability
Prescription
Manufacturer
Janssen Biotech (Johnson & Johnson)
Indications
Crohn's Disease, Ulcerative Colitis
Type
IV Infusion
Doses
Initial dose: 5 mg/kg at weeks 0, 2, and 6, then every 8 weeks
Route
IV infusion
Side Effects
Infusion reactions, infections, headache, abdominal pain
Interactions
May interact with immunosuppressants, live vaccines
Overdose
Infusion reaction, increased infection risk.
Missed Dose
Contact provider to reschedule (IV infusion).
Contraindications
Systemic fungal infections, live vaccines.
Alternatives
Adalimumab, Golimumab, Vedolizumab
Co-Pay Assistance Program
Available
Patient Assistance Program
Available

Frequently Asked Questions

What is Infliximab used for?

Infliximab is used to treat autoimmune diseases such as rheumatoid arthritis, Crohn�s disease, ulcerative colitis, and ankylosing spondylitis by reducing inflammation in the body.

How does Infliximab work?

Infliximab works by blocking the action of tumor necrosis factor (TNF), a protein involved in inflammation, thereby reducing inflammation and immune system activity in autoimmune diseases.

What are the common side effects of Infliximab?

Common side effects include headache, nausea, fatigue, and upper respiratory infections. Serious side effects may include infections, heart failure, and liver damage.

How is Infliximab administered?

Infliximab is administered as an intravenous (IV) infusion in a healthcare setting, typically every few weeks depending on the condition being treated.

Is Infliximab safe during pregnancy?

Infliximab should only be used during pregnancy if the benefits outweigh the risks. Consult your healthcare provider if you are pregnant or planning to become pregnant.

What should I do if I miss a dose of Infliximab?

If you miss a dose, contact your healthcare provider to reschedule your infusion. Do not attempt to make up for a missed dose on your own.

Can Infliximab cause infections?

Yes, Infliximab can suppress the immune system and increase the risk of infections. It is important to monitor for signs of infection and seek prompt medical attention if symptoms arise.

Can Infliximab be used for other conditions?

Yes, Infliximab is used for various autoimmune conditions, including psoriatic arthritis, Crohn�s disease, ulcerative colitis, and ankylosing spondylitis, depending on your doctor�s recommendations.

How long does it take for Infliximab to work?

Infliximab may take several weeks to show noticeable effects, especially for chronic inflammatory conditions like Crohn�s disease or rheumatoid arthritis.

Can Infliximab interact with other medications?

Yes, Infliximab can interact with other medications, especially immunosuppressive drugs. Always inform your healthcare provider about all medications you are taking.